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Five major pregnancy complications were independently associated with heightened long-term risk of peripheral artery disease (PAD), a Swedish cohort study of more than 2 million deliveries found. (Robertson, 7/21)

Oral microbiome dysbiosis and disruption of the oral-gut microbiome network are associated with symptomatic hand osteoarthritis (SHOA), according to a study published online July 21 in RMD Open. (Gotkine, 7/22)

Researchers have developed a fluoride-free gel that could help rebuild damaged tooth enamel, something the body cannot naturally replace once it is lost. Inspired by the proteins that guide enamel formation in infancy, the gel fills microscopic cracks and draws calcium and phosphate from saliva to grow a new mineral layer that closely matches healthy enamel. (7/23)

Phelan-McDermid syndrome (PMS), a genetic neurodevelopmental disorder, has a prevalence of 13.7 per 100,000, according to genetic data from multiple sources in a study published online June 28 in Autism Research. (Gotkine, 7/22)

Treatment with investigational duvakitug appeared to improve remission rates among patients with ulcerative colitis and endoscopic response rates in those with Crohn's disease, results from two cohorts of the phase IIb RELIEVE UCCD trial showed. (Bassett, 7/20)